Which Is Better for an Enlarged Prostate in 2025: HOLEP or TURP?

Enlarged prostate (Benign Prostatic Hyperplasia or BPH) is extremely common in men above 50. It causes symptoms like weak urine flow, frequent night-time urination, burning, urgency, and a constant feeling of not emptying the bladder fully. For decades, TURP was the gold-standard surgery for BPH. But in the last 10–12 years, a newer laser-based treatment — HOLEP — has become increasingly popular.

 

This guide explains the differences in simple language so you can understand which option may be right for you.

1. TURP: The Traditional Approach

TURP is performed through the urinary passage using an electrical cutting loop. It removes small pieces of the enlarged prostate to improve urine flow.

Benefits of TURP

● Trusted procedure used for over 50 years
● Good relief in symptoms
● Works well for small to medium-sized prostates
● Available at most hospitals


Limitations of TURP

● More bleeding compared to laser procedures
● Risk of TUR syndrome (a rare fluid imbalance)
● Longer catheter and hospital stay
● Removes the gland in pieces, not fully
● Higher chance of repeat surgeries in large prostates (>80–100 g)

2. HOLEP: The Modern Laser Option

HOLEP uses a Holmium laser to remove the entire block of enlarged tissue. The tissue is then taken out through a special device called a morcellator. 

Benefits of HOLEP

● Very minimal bleeding
● Works safely for any prostate size — even very large ones (100–300 g)
● Shorter catheter time (usually <2 days)
● Faster recovery and quick return to routine
● Lowest chance of regrowth because the whole blocking tissue is removed
● Safe for patients on blood thinners
● Long-term durability similar to open surgery, without the large incision

Limitations of HOLEP

● Needs a highly trained surgeon and advanced equipment
● Availability varies by hospital and urologist experience

3. HOLEP vs TURP: A Quick Comparison

Feature HOLEP TURP
Bleeding Minimal Moderate
Prostate size Any size Small–medium
Catheter time 2–3 days 4–5 days
Hospital stay 2–3 days 4–5 days
Need for repeat surgery Very low Higher
Safe on blood thinners Yes Usually not
TUR syndrome None Possible
Recovery Fast Moderate
Sexual function Generally preserved Similar outcomes
Cost Slightly higher Lower

4. Is HOLEP Better Than TURP in 2025?

For most patients — yes, HOLEP is a strong option. It is particularly recommended if you have:

  • A large prostate (>80 g)
  • Repeated urinary retention episodes
  • Failed medical treatment
  • Heart history or are on blood thinners
  • Frequent urinary infections due to blockage
  • Poor urine flow despite medications
  • Previous prostate surgery with recurrence

HOLEP is the only endoscopic surgery that completely removes the blocking tissue, similar to open surgery — but with minimal blood loss.

5. What About Sexual Function?

Both HOLEP and TURP can cause retrograde ejaculation (semen flowing backward into the bladder). This is common in most BPH surgeries. However:

  • Erectile function is usually preserved
  • HOLEP in experienced hands has very low risk of incontinence
  • Most men feel their quality of life improves due to better urinary flow

6. Which Surgery Is Safer for Elderly Patients?

For men aged 65–80+, especially those with diabetes, high BP or heart problems:

  • HOLEP is safer due to minimal blood loss
  • Can be done without stopping blood thinners
  • Quicker recovery reduces hospital-related risks

This makes HOLEP the preferred option for older patients.

7. Recovery: What to Expect After Each Surgery

After HOLEP

  • Catheter removed in 2–3 days
  • Mild burning for 5–7 days
  • Light activities from the next day
  • Return to work in 5–7 days
  • Urine flow improves significantly once the catheter is removed

After TURP

  • Catheter stays for 4–5 days
  • Burning for 7–14 days
  • Routine activities in 1–2 weeks
  • Flow improvement may vary depending on how much tissue was removed

8. Cost Comparison (Mumbai Perspective)

Costs vary by hospital category, technology, and prostate size. Although HOLEP costs slightly more upfront, it becomes more economical over time because:

  • Shorter hospital stay
  • Minimal complications
  • Very low chance of needing repeat surgeries
  • Eliminates need for open surgery in large prostates

9. How to Decide Which Surgery Is Right for You

Consider the following:

  • Your age
  • Prostate size
  • Other medical conditions
  • Whether you’re on blood thinners
  • How quickly you want to recover
  • Experience of the surgeon
  • Long-term durability of the result

In simple terms:

  • For medium–large prostates, faster recovery, or blood thinner use → HOLEP wins
  • For smaller prostates and lower cost → TURP works well

10. Conclusion: Why HOLEP Leads in 2025

Across India and globally, HOLEP is now considered the new gold standard — especially for moderate to large prostates. It matches or outperforms TURP in every key aspect:

  • Safety
  • Bleeding
  • Recovery
  • Long-term durability

As more hospitals adopt this technology, HOLEP is expected to replace TURP in most major centres.

Frequently Asked Questions

1. Is HOLEP painful?

No. It is performed under anaesthesia. Mild burning can occur for a few days afterward.

2. Will HOLEP affect my sexual function?

Erections are usually unaffected. Retrograde ejaculation may happen — the same risk exists with TURP.

3. Can HOLEP treat very large prostates?

Yes. Even prostates 150–300 g can be safely treated.

4. Is HOLEP safe for heart patients?

Yes. It is one of the safest options for men on blood thinners.

5. How long do results last?

Because the entire blocking tissue is removed, HOLEP offers long-lasting relief with almost no repeat
surgeries needed.